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http://ir.juit.ac.in:8080/jspui/jspui/handle/123456789/9382| Title: | Sodium Dodecyl Sulphate-Supported Nanocomposite as Drug Carrier System for Controlled Delivery of Ondansetron |
| Authors: | Sharma, Gaurav Naushad, Mu. Thakur, Bharti Kumar, Amit Negi, Poonam Saini, Reena Chahal, Anterpreet Kumar, Ashok Stadler, Florian J. Aqil, U.M.H. |
| Keywords: | Sodium dodecyl sulphate Nanocomposite Drug delivery Ondansetron |
| Issue Date: | 2018 |
| Publisher: | Jaypee University of Information Technology, Solan, H.P. |
| Abstract: | Sodium dodecyl sulphate-supported iron silicophosphate (SDS/FeSP) nanocomposite was successfully fabricated by the co-precipitationmethod. The SDS/FeSP nanocompositewas investigated as a drug carrier for ondansetron. The cumulative drug release of ondansetron was observed at various pH values for different time intervals, i.e., from 20 min to 48 h. A ranking of the drug release was observed at different pHs; pH 2.2 > saline (pH 5.5) > pH 7.4 > pH 9.4 > distilled water. Maximum release of encapsulated drug was found to be about 45.38% at pH 2.2. The cell viability tests of SDS/FeSP nanocomposite concluded that SDS/FeSP nanocomposite was non-cytotoxic in nature. |
| URI: | http://ir.juit.ac.in:8080/jspui/jspui/handle/123456789/9382 |
| Appears in Collections: | Journal Articles |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Sodium Dodecyl Sulphate-Supported Nanocomposite as Drug Carrier System for Controlled Delivery of Ondansetron.pdf | 2.96 MB | Adobe PDF | View/Open |
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