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http://ir.juit.ac.in:8080/jspui/jspui/handle/123456789/9190
Title: | UniDrug-Target: A Computational Tool to Identify Unique Drug Targets in Pathogenic Bacteria |
Authors: | Chanumolu, Sree Krishna Rout, Chittaranjan Chauhan, Rajinder S. |
Keywords: | Pathogenic Bacteria UniDrug-Target |
Issue Date: | 2012 |
Publisher: | Jaypee University of Information Technology, Solan, H.P. |
Abstract: | Targeting conserved proteins of bacteria through antibacterial medications has resulted in both the development of resistant strains and changes to human health by destroying beneficial microbes which eventually become breeding grounds for the evolution of resistances. Despite the availability of more than 800 genomes sequences, 430 pathways, 4743 enzymes, 9257 metabolic reactions and protein (three-dimensional) 3D structures in bacteria, no pathogenspecific computational drug target identification tool has been developed. |
URI: | http://ir.juit.ac.in:8080/jspui/jspui/handle/123456789/9190 |
Appears in Collections: | Journal Articles |
Files in This Item:
File | Description | Size | Format | |
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UniDrug-Target a computational tool to identify unique drug targets in pathogenic bacteria.pdf | 604.05 kB | Adobe PDF | View/Open |
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