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http://ir.juit.ac.in:8080/jspui/jspui/handle/123456789/9012Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Thakur, Raman | - |
| dc.contributor.author | Anand, Rajesh | - |
| dc.contributor.author | Tiwari, Shraddha | - |
| dc.contributor.author | Singh, Agam | - |
| dc.contributor.author | Tiwary, Bhupendra N. | - |
| dc.contributor.author | Shankar, Jata | - |
| dc.date.accessioned | 2023-01-06T09:34:10Z | - |
| dc.date.available | 2023-01-06T09:34:10Z | - |
| dc.date.issued | 2015 | - |
| dc.identifier.uri | http://ir.juit.ac.in:8080/jspui/jspui/handle/123456789/9012 | - |
| dc.description.abstract | InvasiveaspergillosiscausedbyAspergillusspecies(Aspergillusfumigatus,A.flavus,andA.terreus)islife-threateninginfectionsinimmunocompromisedpatients.UnderstandingtheinnateandadaptiveimmuneresponseparticularlyT-helpercells(TH-cells)againsttheseAspergillusspeciesandhowthedifferentsub-setofTH-cellsareregulatedbydifferentiatingcytokinesatprimarytargetorgansitelikelung,kidneyandbrainisofgreatsignificancetohumanhealth.ThisreviewfocusesonpresentationofAspergillusthroughAntigenpresentingcells(APCs)tothenaiveCD4+T-cellsinthehost.Theproductionofdifferentiating/effectorcytokinesthatactivatefollowingTH-cells,e.g.,TH1,TH2,TH9,andTH17hasbeenreportedinassociationoraloneinallergicorinvasiveaspergillosis.Chemokines(CXCL1,CXCL2,CCL1,andCCL20)andtheirreceptorsassociatedtotheseTH-cellshavealsobeenobservedininvasiveaspergillosis.Thus,furtherstudyoftheseTH-cellsininvasiveaspergillosisandotherelementsofadaptiveimmuneresponsewithAspergillusspeciesarerequiredinordertohaveabetterundersandingofhostresponseforsaferandeffectivetherapeuticoutcome. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Jaypee University of Information Technology, Solan, H.P. | en_US |
| dc.subject | Cytokines | en_US |
| dc.subject | Dendriti cells | en_US |
| dc.subject | Aspergillus | en_US |
| dc.subject | Antigen presenting cells | en_US |
| dc.title | CytokinesinduceeffectorT-helpercellsduringinvasiveaspergillosis;whatwehavelearnedaboutT-helpercells | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | Journal Articles | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Cytokines induce effector T-helper cells during invasive aspergillosis what we have learned about T-helper cells.pdf | 775.12 kB | Adobe PDF | View/Open |
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