Effect of quercetin on micellization behaviour of Tween-20 in hydro-ethanolic solvent system: An electrolyte induced thermodynamic study

Abstract

The thermodynamic studies for non-ionic surfactant Tween-20 has been performed in presence of a well known flavonoid quercetin. The conductivity studies have been carried out with different concentrations of quercetin in 30% v/v ethanolic solution at five different temperatures (20 oC to 40 oC with difference of 5 oC). Since Tween-20 is non-ionic in nature, 1% w/v sodium chloride solution has been added as an electrolyte. Critical micelle concentration (CMC) and XCMC values as a function of temperature have been determined from conductance studies. Furthermore, various thermodynamic parameters viz. change in enthalpy (ΔHo m), entropy (ΔSo m) and Gibb’s free energy (ΔGo m) of micellization have been calculated. Overall, the changes in micellization process of Tween-20 in presence of quercetin has been studied and reported.