Study on Natural Antimicrobial Compounds Against Bacterial Isolates

Abstract

Microbes are present everywhere in the environment and that can be disease causing or non disease causing . The chemical antimicrobials used commonly have several side effects on human health as well as on the environment and also the microbes are developing resistance against the present chemical antimicrobials that is why the use of herbal compounds as antimicrobials have great importance . In this study we used three herbal compounds that are Terminilia Arjuna , Tamarindus Indica and Withania somnifera and checked there antimicrobial activity against the bacterial isolates , isolated from environment of three different areas from the university ,using the antimicrobial assay with extracts prepared from these compounds by cold maceration method in which methanol was used as an extraction solvent . The biofilms of these bacterial isolates were grown to check the biofilm forming potential of these compounds. The results of this study showed that the herbal compounds used have a significant amount of antimicrobial activity at higher concentration . Also the bacterial isolates used have great potential to form biofilms and the antibiofilm activity of these compounds can also be checked . In future the antimicrobial and antibiofilm activity against more bacterial isolates with more herbal compounds can also be checked