Meta Analysis of Brain and Central Nervous System Cancer Microarray Datasets

Abstract

The lack of specific treatment for different types and stages of Brain and Central Nervous System cancer lead to an increase mortality rate. In many common types of Brain and Central Nervous System cancers, various bio-markers have been identified but they are not tested clinically due to their low specificity and/or sensitivity. Through this project we have predicted the potential bio-markers in Brain and CNS cancers using meta-analysis and the functional analysis of these potential genes has been done in terms of metabolic and cellsignalling pathways.