Interaction Of Metal Nano Particles With Protein: A Spectroscopic Study To Monitor Protein Conformational Changes

Abstract

Nanoparticles (NPs) are those objects ranging in size from 1-100nm so because of their varying sizes they differ from there bulk materials in properties. There properties are unique because of which they may be suitable in distinct range of applications and wherefore they have attached significant notice specifically in the field of biomedical. The application of nanodrugs, nanovaccines and nanoparticles are being entirely examined. In spite, our understanding about the biocompatibility and hazards of exposure to nanomaterials is precise, so exposure to these nanomaterials for humans can be coincidental, for example occupational exposure or voluntarily like the use of nano-enabled consumer commodities.There are an rising count of investigations that exhibit unfavorable effects of nanomaterials in in-vitro cellular systems, but it is uncertain whether the accessible data can be reliably anticipated to conclude the adverse effects of nanobiotechnology for humans. Hence, there is an urgent need to understand the molecular mechanisms of nanoparticles to biological system interaction.