Please use this identifier to cite or link to this item: http://ir.juit.ac.in:8080/jspui/jspui/handle/123456789/6379
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dc.contributor.authorDutta, Sumita-
dc.contributor.authorRout, Chittaranjan [Guided by]-
dc.date.accessioned2022-09-22T10:04:57Z-
dc.date.available2022-09-22T10:04:57Z-
dc.date.issued2017-
dc.identifier.urihttp://ir.juit.ac.in:8080/jspui/jspui/handle/123456789/6379-
dc.description.abstractTherapeutic efficacy of a drug depends on the solubility of the core compound. According to IUPAC, solubility refers to the proportion of a chosen substance in designated solvent. The dissolution of a drug compound is dependent on its structure and solution conditions. Structure of a molecule decides crystal properties ,mostly physicochemical , which determine aqueous solubility[1]. Mixes with poor dissolution convey a higher risk of failure during discovery and development since inadequate dissolvability might trade off alternative property measures, veil additional unwanted properties, impact each pharamacological approach of the compound, and lastly might influence production capability of the compound. Potential difficulties rising from poor solubility: - cut-back target specificityen_US
dc.language.isoenen_US
dc.publisherJaypee University of Information Technology, Solan, H.P.en_US
dc.subjectSolubilisation processen_US
dc.subjectDatawarrioren_US
dc.subjectScatter Ploten_US
dc.subjectRegression Outputen_US
dc.titleCorrelating Activity of Drugs With Low Solubility Using Qsar and Qspr Modelsen_US
dc.typeProject Reporten_US
Appears in Collections:B.Tech. Project Reports

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