Differential Expression of miR 127 IN Lung Cancer

Abstract

Cancer is a complex disease in which cells in a specific tissue are no longer fully responsive to the signals within the tissue that regulate cellular differentiation, survival, proliferation and death. As a result, these cells accumulate within the tissue, causing local damage and inflammation and in later stage metastasize throughout the body. There are over 200 different types of cancer [1]. The risks factors leading to the development of cancer diverse and not yet completely understood. These may include environmental pollutants, tobacco, dietary factors, radiation exposure, certain infections, viruses, etc [2]. In 2012, 14.1 million adults in the world were diagnosed with cancer and there were 8.2 million deaths from cancer in the world in 2012 [3].